PREVENT Cole 30 tablets
To reduce cholesterol levels
When cholesterol levels exceed the reference range, the walls of arteries are impaired with a subsequent increase in the risk of cardiac diseases, such as infarction, ischaemia and cerebral stroke.
Hypercholesterolaemia does not cause symptoms but manifests when the health of coronary arteries is already seriously impaired.
As a rule of thumb, the term hypercholesterolaemia indicates plasma cholesterol levels higher than 180-200 mg/dL.
Recommended LDL levels can be in the range of 130 and 160 mg/dL.
Recommended HDL levels must be in excess of 60 mg/dL.
HDL values below 35 mg/dL are associated with an increased risk of atherosclerosis.
COMBINED ACTIVE HYPOLIPIDEMIC AGENTS
Dosage: 1-2 tablets in the evening before going to bed
The European Regulation for health slogans enforced on 14 December 2012 establishes that only foods containing red rice that allow a daily intake of 10 mg of monacolin K can make the following claim,
«Monacolin K of red rice contributes to maintain normal cholesterol levels in the blood».
Fermented red rice stimulates metabolic efficiency of the liver and modulates cholesterol synthesis.
produced by fermentation of rice (Oryza sativa) with Monascus Purpureus, a yeast.
Fermentation promoted by this microorganism yields several substances, including the typical red pigment, the component “of EXCELLENCE” of red rice, which is made up of MONACOLIN K.
HAS POWERFUL CHOLESTEROL LOWERING properties
Based on a known study published in the American Journal of Nutrition (1999), the cholesterol reducing effect of 5 mg of monacolin K was identical to that of 10-20 mg of lovastatin.
Monacolin - mechanism of action
Blocks endogenous synthesis of cholesterol
Cholesterol lowering action and inhibition of Q10 synthesis
PREVENT COLE with COENZYME Q10 10 mg
This physiological constituent of our body intervenes in oxidation-reduction reactions involved in ATP (adenosine triphosphate) synthesis.
Coenzyme Q10 presents antioxidant properties and inhibits LDL cholesterol oxidation, the pathological key to atherosclerosis.
Glycaemic Index lowering action
CHROMIUM PICOLINATE has a hypoglycaemic effect.
Chromium is a micronutrient that, present in traces in our body, plays an important role as cofactor in strengthening insulin function.
Though the precise mechanism of action has as yet to be precisely defined, chronic Chromium deficiency reduces the body’s sensitivity to insulin, increases cholesterol and impairs immune defences.
It is used in the Picolinate form because this salt ensures excellent bioavailability in terms of actual absorption of Chromium.
- stimulates the activity of enzymes involved in glucose metabolism, which is useful for energy and for the synthesis of fatty acids;
- Provenly enhances insulin efficacy and its glucose manipulating capacity, thus preventing hypoglycaemia or diabetes;
- moreover, several studies indicate that chromium encourages a reduction in total cholesterol and LDL cholesterol levels, and improves body composition.
Reduced cardiovascular risk
When blood cholesterol levels become abnormally high, fat deposits made up of cholesterol and calcium have a tendency to build up in the arteries, including those of the heart, with a subsequent increase in the possible occurrence of heart attacks and other complications.
Folic Acid and B Group Vitamins reduce homocysteine levels, a factor that is related to the cardiovascular risk.
- Homocysteine is an amino acid that is normally produced in the body from methionine, an essential amino acid which we introduce into our body with food.
- The homocysteine produced is then converted back into methionine.
- If the homocysteine that is not transformed builds up in the body, it can be harmful for various organs and, particularly, for cardiovascular system function.
Artichoke extract has a protective action on the liver.
It considerably inhibits cholesterol synthesis especially by inhibiting the enzyme HMG-CoA reductase. In 2000, a well-known scientific experiment was conducted by German researchers on 150 adults with total cholesterol levels in excess of 280 mg/dL. Participants administered supplementation with artichoke leaf extract observed a 23% reduction in LDL cholesterol, compared to 6% in the control group that had taken a placebo.
Statins (pravastatin, atorvastatin, cerivastatin, fluvastatin) are among the most effective medicines for total and LDL cholesterol reduction.
Statins (HMG-CoA reductase inhibitors) inhibit cholesterol production in the liver by blocking the hepatic enzyme that is responsible for the production of cholesterol.
Results worthy of note are recorded already after a couple of weeks from the start of the treatment and peak after 30-40 days.
Side effects of statin
Hepatic damage: in some cases, statins can cause an increase in hepatic enzymes.
Muscle problems: statins can cause muscle pain and discomfort (statin-induced myopathy)
Coenzyme Q10 intervenes in oxidation and reduction processes.
An essential part of the cellular machine that produces ATP
Its deficiency can cause myopathy.